Lean body mass is at the heart of strength, metabolism, mobility, and long-term health. But why do some people naturally have more muscle than others, despite similar diets or exercise routines?
A recent study in Genome Biology explored this question in depth using whole-genome sequencing. The study contrasted the genetic data of over 85,000 people from diverse ancestries to identify which genes influence lean body mass. Scientists found several genetic variants that impact how the body builds and maintains muscle tissue – and most of them were previously unknown.
While the genetics are complex, here’s what we know for sure: how we develop or sustain muscle isn’t solely about effort. Genetics play a part too. And understanding your muscle mass is key to monitoring overall health, especially as we age.
The study used DEXA scan findings as a reliable marker for the evaluation of lean mass. That is because DEXA is still the gold standard for measuring body composition. It can tell you how much of your body is fat, how much is muscle, and in what ratio that happens in various regions of your body – arms, legs, trunk, and so on. Such detail is important when studying the correlation between genes and physical traits.
To the folks at Accurate Imaging Diagnostics, this study reinforces that which we see on a daily basis. All the patients come in with the same goal, the same desire – get healthier, lose weight, get stronger – but with varying results. DEXA takes some of the speculation out of those processes, providing acute, quantifiable results. Whether you’re starting an exercise routine, suffering from an illness, or just wanting to age healthily, your lean body mass is a figure you should have on hand.
This study also enables one to bypass crude weight or BMI to a more meaningful measurement: what your body is made of. Two people might weigh the same, but one is more muscular, less fat. Without DEXA, none of those differences are evident.
The genetics of lean body mass remain to be unveiled – but your current body composition can be measured today, safely and in an instant.
A DEXA scan takes about 15 minutes, requires no preparation, and gives you the entire story. We offer these scans at our Thornhill clinic, seeing patients from across the GTA. If you’re ready to know what’s really happening in your body – not just on the scale – a DEXA scan is a smart starting point.
To book your appointment or inquire further, contact (905) 709-3939 or visit accurateimagingdiagnostics.com.
Reference:
Liang Y, et al. Multi-ancestry whole-genome sequencing analysis of lean body mass. Genome Biology. 2024.
